Biopharmaceutics and Pharmacokinetics

Name: Biopharmaceutics and Pharmacokinetics
Availability: InStock
ISBN: 9789386211637

Par V. Venkateswarlu

Publié par Pharmamed Press

English 2020 ISBN 9789386211637

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À propos de ce livre

<div>About the Book This book deals with the basics of the two disciplines of biopharmaceutics and pharmacokinetics. Different factors such as biological, physiochemical and formulation that influence the therapeutic efficacy of a drug are covered in biopharmaceutics. The absorption, distribution, metabolism and excretion of drugs are studied under this subject. Salient Features  • Basics of biopharmaceutics and pharmacokinetics help to understand the various procedures and advances in drug design, product development, therapeutic drug monitoring, etc. • Pharmacokinetics covers the fundamentals of one compartment open model, multi-compartmental models. One compartment open model is presented in an elaborate manner to make the students familiar with various aspects of pharmacokinetics  • Mathematical equations are developed using simple integration and differentiation methods  • Practice problems are provided wherever necessary, and a question bank is included at the end of each chapter  • Extreme care has been exercised to present the concepts in a simple way Second Edition includes  • Application of principles in formulation development in industry for successful bioequivalence studies is included  • One chapter on “In-vitro Dissolution Testing” is included to evaluate test formulations to chose right product for bioequivalence studies • A chapter on biostatistics with practice problems is included Contents 1. Introduction to Biopharmaceutics 2. Absorption of Drugs from Gastrointestinal Tract 3. Drug Distribution 4. Drug Elimination 5. Pharmacokinetics: Basic Concepts 6. One Compartment Open Model 7. Multi-Compartment Models 8. Multiple-Dose Regimens 9. Non-linear Pharmacokinetics 10. Non-compartmental Pharmacokinetics 11. Bioavailability and Bioequivalence 12. Biostatistics 13. In-vitro Dissolution Testing About the Author V. Venkateswarlu is presently working as Senior Director, Dr.Reddys's Laboratories Ltd.,Hyderabad. Currently he is heading Biostudies and Europe product development teams of Dr.reddy's Laboratories. He worked as an Associate Professor, University College of Pharmaceutical Sciences, Kakatiya University, Warangal before joining in industry. He did M. Pharm., from Birla Institute of Technology, Ranchi and PhD from Kakatiya University, Warangal. He also got Post-Doctoral Fellowship from University of Georgia Athens USA. He has 27 years of teaching experience including 12 years postgraduate teaching, besides 13 years of research experience.</div>