A Comprehensive Book on Experimental Pharmaceutics

About the Book: How often we find ourselves struck while performing practicals and experiments related to formulation of dosage forms, where the doubts related to selection of ingredients, evaluation parameters and also during final compilation of results as tables and figures. This book aims at providing the state of the art information about formulation, excipients, analysis and operating procedures in the simplest of the way to make formulation and understanding of the subjects easy. This book contains basic principles of experiments along with procedures for carrying them out. The contents vary from experimental details, UV-TLC analysis of drugs and dosage forms, release kinetics graphs and calculations, optimisation techniques, standard operating procedures, IR of commonly used drugs, polymer and surfactants detail, systems of weights and measures and information about often used drugs. The exclusive feature of this book is incorporation of experiments related to formulation along with the estimation of pharmacokinetic properties of drugs based on biological samples. Contents: Experiment – 1: Hydrotropy StudiesExperiment – 2: Drug Excipient Incompatibility StudiesExperiment – 3: Solid DispersionsExperiment – 4: Film Coated TabletsExperiment – 5: Effect of Surfactant on In Vitro Drug ReleaseExperiment – 6: Floating TabletExperiment – 7: Comparison of Antacid ActivityExperiment – 8: Evaluation of Packaging MaterialExperiment – 9: Estimation of Pharmacokinetic ParametersExperiment – 10: Estimation of Pharmacokinetic Parameters by Urinary Excretion MethodExperiment – 11: Estimation of Protein BindingExperiment – 12: Bioequivalence Study of ParacetamolExperiment – 13: Gel FormulationExperiment – 14: Microspheres by Solvent Evaporation MethodExperiment – 15: Alginate BeadsExperiment – 16: Transdermal Delivery System (Reservoir Type)Experiment – 17: Transdermal Delivery System (Matrix Type)Experiment – 18: Muco-adhesive TabletsExperiment – 19: LiposomesExperiment – 20: NiosomesExperiment – 21: Solid Lipid NanoparticlesExperiment – 22: Multiple EmulsionsExperiment – 23: Fast Dissolving TabletsExperiment – 24: OcusertsExperiment – 25: Chewable TabletsExperiment – 26: Nano SuspensionsExperiment – 27: Bilayer TabletsExperiment – 28: Film Forming Polymeric SolutionsExperiment – 29: Bioadhesive GelExperiment – 30: Dissolution Media SelectionExperiment – 31: In Vitro Rate of Absorption DeterminationExperiment – 32: In Vitro In Vivo CorrelationExperiment – 33: Drug Release KineticsExperiment – 34: Preformulation StudiesExperiment – 35: Sterile Ophthalmic PreparationsExperiment – 36: pH Partition HypothesisExperiment – 37: Enteric TabletsExperiment – 38: Calibration and Validation of Laboratory EquipmentExperiment – 39: Spectroscopic Estimation of DrugsExperiment – 40: Thin Layer Chromatography Estimation of DrugsExperiment – 41: FTIR of Common DrugsExperiment – 42: General Polymers Used in PharmaceuticalsExperiment – 43: Common surfactants with HLB Values and UseExperiment – 44: Typical Release Kinetic Equations and PlotsExperiment – 45: General Optimisation TechniquesExperiment – 46: Different Systems of Weights and MeasuresExperiment – 47: Drugs and their General PropertiesExperiment – 48: Standard Operating Procedures (SOPs) About the Authors: Mousumi Kar, M.Pharm, PhD, MBA, is an academician with a researchers outlook and presently working as Professor in Pharmaceutics at IPS Academy College of Pharmacy, Indore. She has to her credit many national and international publications in various journals of repute. A reviewer of many international online and print journals, she is life member of Association of Pharmaceutical Teachers of India. Her biography was included in Marquies whos who edition. She has one candidate awarded with PhD under her guidance, and two doctoral candidates who are researching on novel drug delivery systems for different drugs. Her area of expertise is development of drug delivery systems for synthetic and herbal drugs. Sujit Pillai, M.Pharm, PhD did his masters from Manipal University and doctorate from MLS University, Udaipur. He is currently serving as Professor and Principal in GRY Institute of Pharmacy, Borawan, Madhya Pradesh. He has to his credit many research publications in national and international journals. He is receipt of research grant from DST and MPCoST. His research activity is focused on analytical method development. He has guided a number of post graduate students and presently guiding 04 students towards their doctoral degree along with a doctoral awardee. He holds a thorough understanding of analytical techniques for estimation.