Experimental Organic and Medicinal Chemistry: Principles and Practice, Second Edition

“Experimental Organic and Medicinal Chemistry: Principles and Practice, 2nd Edition.” of this comprehensive guide. Designed for pharmacy and allied field graduates, this book, "Experimental Organic and Medicinal Chemistry-Principles & Practice," is a treasure trove of synthetic and analytical approaches essential for both academic and industrial realms. Embark on a journey through 64 enlightening chapters, where the art of synthesizing drugs and drug intermediates is unveiled alongside their pharmaceutical significance and underlying reaction mechanisms. Delve into the realm of green synthetic strategies, where alternative reagents and safety precautions take center stage, promising a sustainable approach to drug synthesis.          From conducting limit tests to qualitative analyses of diverse compounds, this book intricately details organic-medicinal compound estimations, active principle isolations, and the nitty-gritty of general laboratory practices. With a reader-friendly approach to complex experiments that require no specialized equipment, this book is a must-have for anyone seeking a deeper understanding of the nuanced world of Experimental Organic and Medicinal Chemistry. Table of Contents Overview: Contents: 1.     Laboratory Practices 2.     Laboratory Safety 3.     Acylation 4.     Alkylation 5.    Aromatic Electrophilic Subsitution 6.    Beckmann Rearrangement 7.    Bernthsen Synthesis 8.    Biginelli Synthesis 9.    Biltz Synthesis 10. Borsche-Drechsel Cyclization 11. Claisen Isoxazole Synthesis 12. Claisen-Schmidt Reaction 13. Diazotization Reaction 14. Erlenmeyer-Plochl Azlactone Synthesis 15. Fischer Indole Synthesis 16. Fischer-Speier Esterification 17. Haloform Reaction 18. Hantzsch 1,4-Dihydropyridine Synthesis 19. Hydrolysis 20. Knoevenagel Condensation 21. Mannich Reaction 22. Oxidation 23. Paal-Knorr Pyrazole Synthesis 24. Paal-Knorr Pyrrole Synthesis 25. Paal-Knorr Thiophene Synthesis 26. Pechmann Reaction 27. Perkin Synthesis 28. Phillips Reaction 29. Quinoxaline Synthesis 30. Radziszewski Reaction 31. Reduction 32. Reimer-Tiemann Reaction 33. Schiff Base Synthesis (Nucleophilic Addition Reaction) 34. Skraups Synthesis 35. Sulphonamide Synthesis 36. Sulphonate Ester Synthesis (Nucleophilic Substitution Reaction, SN1) 37. Uracil Synthesis 38. Vilsmeier-Haack Reaction 39. VON Baeyer Synthesis 40. Williamson’s Ether Synthesis (Nucleophilic Substitution of alkaliode/aryloxide SN2) 41. Wohl-Ziegler Reaction 42. Semi Quantitative Analysis QUALITATIVE ANALYSIS 43. Analysis of Inorganic Compounds 44. Analysis of Organic Compounds TITRIMETRIC ANALYSIS 45.   Estimation of Drugs by Acid-Base Titration 46. Estimation of Drugs by Non-Aqueous Titration 47. Estimation of Drugs by Diazotization Titration 48. Estimations of Drugs by Redox Titration NATURAL PRODUCTS CHEMISTRY 49. Isolation of Plant Alkaloids 50. Isolation of Milk Proteins 51. Isolation of Carbohydrates 52. Isolation of Essential Oils 53. Isolation of Glycosides 54. Isolation of Flavanoids 55. Isolation of Terpenoids 56. Qualitative Analysis of Carbohydrates 57. Qualitative Analysis of Amino Acids and Proteins 58. Qualitative Analysis of Alkaloids 59. Qualitative Analysis of Steroids 60. Qualitative Analysis of Terpenes and Terpenoids 61. Qualitative Analysis of Glycosides 62. Physicochemical Characterization of Natural Products 63. Quantitative Determination of Natural Products 64. Degradation of Natural Products About the Authors / Biographies: About the Authors: T. Durai Ananda Kumar, M. Pharm, Ph.D., is working as an Associate Professor, in the Department of Pharmaceutical Chemistry, JSS College of Pharmacy (a constituent College of JSS Academy of Higher Education and Research), Udhagamandalam, Tamil Nadu. He has teaching experience on Medicinal Chemistry, Computer-Aided Drug Design, Food analysis and Herbal and cosmetic analysis for B. Pharmacy and M. Pharmacy students. He has guided research projects on the structure-based drug design (SBDD) and chemometrics approaches for pharmacy graduates. He has published write number here research articles in peer reviewed journals and has authored six books titled, Elementary Pharmacoinformatics, Experimental Organic Medicinal Chemistry-Principles and Practice, Microwave Assisted Chemistry Experiments (Organic Synthesis, Chemical synthesis & extraction), Current concepts in drug design, Computer aided drug development and Drug design-a conceptual overview. He is on editorial board and reviewer for peer reviewed biomedical journals. The author is life member of Association of Pharmaceutical Teachers of India (APTI) and registered pharmacist of Tamil Nadu State Pharmacy Council.N. Swathi, M. Pharm., Ph.D., is working Professor in the Department of Pharmaceutical Chemistry, Gokaraju Rangaraju College of Pharmacy, Hyderabad, Telangana. She has 20 years of teaching experience and taught Pharmaceutical Organic Chemistry, Medicinal Chemistry, Instrumental Methods of Analysis, Computer-aided drug design, Modern Pharmaceutical Analytical Techniques, and Computer-aided drug development subjects for B. Pharmacy and M. Pharmacy students. Molecular modeling, synthesis and evaluation of glitazones and analytical method development were few of her research interests. She has guided twenty-four M. Pharmacy (Pharmaceutical Chemistry and Pharmaceutical Analysis) students for their dissertation work. She has twenty-nine research publications in peer reviewed national and international journals. She is a reviewer for Medicinal Chemistry Research, Springer. She has authored three books titled, Experimental Organic Medicinal Chemistry-Principles and Practice, Microwave Assisted Chemistry Experiments (Organic Synthesis, Chemical synthesis & extraction) and Computer aided drug development. She is a registered pharmacist in Andhra Pradesh State Pharmacy Council and a Life member of Association of Pharmaceutical Teachers of India.