The Chemistry of Organic Medicinal Products

Medicinal chemistry became more and more the study of the chemical reactions between therapeutic agents and living tissues. Appreciable progress is made, and a book on medicinal chemistry perforce, takes cognizance of the stimulating developments.This edition is completely revised. The chemical classification of medicinal agents has been retained. Typical syntheses of important medicinal agents have been included, along with a description of properties. Correlations between chemical structure and physiological activities are pointed out. Wherever possible, protoplasmic reactions are indicated. The separate chapter on antibiotics has been added.It is anticipated, that where the book is used in the class room the text will be amplified and expanded by the instructor, and that where it is used for reference purposes the literature citations may lead the student or investigator to additional sources of information. Contents 1.      Compounds composed of Carbon and Hydrogen2.      Compounds composed of Carbon, Hydrogen and Halogen3.      Hydroxyl Derivatives of Hydrocarbons4.      Ethers and Ether Peroxides5.      Carbonyl Group6.      Carboxyl Group7.      Amines and Amine Derivatives8.      Cyanides and Nitro Compounds9.      Sulfur Compounds10.  Compounds of Phosphorus, Arsenic, and Antimony11.  Cycles Containing one Heteroatom12.   Cycles with Two or More Heteroatoms13.  Stereoisomerism14.  Antibiotics15.  Organometallic Compounds and Metal Salts      16. Some Physicochemical Properties of Medicinal Products About the Authors Glenn L. Jenkins, is Professor of Pharmaceutical Chemistry and Dean of the School of Pharmacy, Purdue University.Walter H. Hartung, is Professor of Pharmaceutical Chemistry Medical College of Virginia.Kenneth E. Hamlin, Jr., is Assistant Director of Chemical Research Abbott LaboratoriesJohn B. Data, is Associate professor of Pharma